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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
20.61
Human Site:
S550
Identified Species:
34.87
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
S550
P
E
M
P
T
L
E
S
L
S
E
P
G
V
P
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S550
P
E
M
P
T
L
E
S
L
S
E
P
G
V
P
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
S556
P
E
M
P
T
L
E
S
L
S
E
P
G
V
P
Dog
Lupus familis
XP_538417
666
74288
S555
P
D
V
P
T
L
E
S
L
L
E
P
G
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
S551
P
E
M
P
T
L
E
S
L
S
P
P
G
V
P
Rat
Rattus norvegicus
Q66HE5
630
69934
S529
T
A
P
S
T
F
G
S
L
D
Q
L
A
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
A550
P
D
P
P
A
P
E
A
M
E
E
A
V
G
P
Chicken
Gallus gallus
Q9IA88
798
88848
F542
T
A
R
M
T
S
A
F
L
A
S
Q
S
D
A
Frog
Xenopus laevis
NP_001088596
570
64876
P469
N
M
H
G
G
F
L
P
R
D
R
T
S
S
S
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
G872
L
K
V
P
G
L
E
G
Y
G
L
S
Y
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
T1173
E
S
E
S
E
G
T
T
T
A
T
N
M
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S716
Q
Y
M
N
Q
L
T
S
S
T
M
M
S
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
V410
P
R
E
I
M
N
E
V
L
K
A
L
Q
E
L
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
L529
I
Y
I
A
L
K
N
L
G
A
E
W
A
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
93.3
26.6
N.A.
33.3
13.3
0
20
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
33.3
N.A.
53.3
20
0
33.3
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
8
0
8
8
0
22
8
8
15
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
0
15
0
0
0
8
0
% D
% Glu:
8
29
15
0
8
0
58
0
0
8
43
0
0
8
0
% E
% Phe:
0
0
0
0
0
15
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
15
8
8
8
8
8
0
0
36
15
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
8
0
0
0
15
0
% K
% Leu:
8
0
0
0
8
50
8
8
58
8
8
15
0
0
15
% L
% Met:
0
8
36
8
8
0
0
0
8
0
8
8
8
0
0
% M
% Asn:
8
0
0
8
0
8
8
0
0
0
0
8
0
0
0
% N
% Pro:
50
0
15
50
0
8
0
8
0
0
8
36
0
0
58
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
8
8
8
0
8
% Q
% Arg:
0
8
8
0
0
0
0
0
8
0
8
0
0
0
0
% R
% Ser:
0
8
0
15
0
8
0
50
8
29
8
8
22
22
8
% S
% Thr:
15
0
0
0
50
0
15
8
8
8
8
8
0
0
0
% T
% Val:
0
0
15
0
0
0
0
8
0
0
0
0
8
29
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _